DE, de, or dE may refer to:

Language

• "De" is a preposition meaning "of" or "from" in a number of Romance Languages such as French and Spanish, and is often evident in the names of people, places, and things
• De (Cyrillic), a letter in the Cyrillic alphabet
• "De", a particle of nobility in French names.
• "De", the Dutch article for both male and female words.
• "De", the Hungarian word for "But"

Codes

• "DE", Germany (ISO 3166-1 alpha-2 country code, from German Deutschland)
• "DE", German language (ISO 639 alpha-2, from German Deutsch)
• Delaware (U.S. state postal symbol)
• "DE", IATA airline designator for Condor Airlines